Table 1 Demographic characteristics of TCGA samples.
| Â | LN-negative | LN-postive | p |
|---|---|---|---|
N | 128 | 115 | Â |
Race (%) | Â | Â | 0.355 |
   NA | 3 (2.3) | 0 (0.0) |  |
   American Indian or Alaska native | 0 (0.0) | 1 (0.9) |  |
   Asian | 6 (4.7) | 5 (4.3) |  |
   Black or African American | 23 (18.0) | 17 (14.8) |  |
   White | 96 (75.0) | 92 (80.0) |  |
Number of positive lymphnodes by HE (mean (sd)) | 0.00 (0.00) | 7.13 (5.71) | <0.001 |
Progesterone receptor status (%) | Â | Â | 0.035 |
   NA | 9 (7.0) | 10 (8.7) |  |
   Indeterminate | 0 (0.0) | 1 (0.9) |  |
   Negative | 54 (42.2) | 29 (25.2) |  |
   Positive | 65 (50.8) | 75 (65.2) |  |
Estrogen receptor status (%) | Â | Â | 0.01 |
   NA | 8 (6.2) | 10 (8.7) |  |
   Indeterminate | 0 (0.0) | 1 (0.9) |  |
   Negative | 46 (35.9) | 20 (17.4) |  |
   Positive | 74 (57.8) | 84 (73.0) |  |
HER2 immunohistochemistry receptor status (%) | Â | Â | 0.026 |
   NA | 15 (11.7) | 26 (22.6) |  |
   Equivocal | 28 (21.9) | 12 (10.4) |  |
   Indeterminate | 0 (0.0) | 1 (0.9) |  |
   Negative | 69 (53.9) | 57 (49.6) |  |
   Positive | 16 (12.5) | 19 (16.5) |  |
Therapy types (%) | Â | Â | 0.019 |
   NA | 36 (28.1) | 24 (20.9) |  |
   Ancillary | 1 (0.8) | 1 (0.9) |  |
   Chemotherapy | 55 (43.0) | 73 (63.5) |  |
   Chemotherapy and hormone therapy | 0 (0.0) | 1 (0.9) |  |
   Hormone therapy | 34 (26.6) | 12 (10.4) |  |
   Immunotherapy | 1 (0.8) | 1 (0.9) |  |
   Targeted molecular therapy | 0 (0.0) | 1 (0.9) |  |
   Other | 1 (0.8) | 2 (1.7) |  |
Pathologic stage (%) | Â | Â | <0.001 |
   Stage II | 3 (2.4) | 1 (0.9) |  |
   Stage IIA | 106 (82.8) | 8 (7.0) |  |
   Stage IIB | 15 (11.7) | 26 (22.6) |  |
   Stage III | 0 (0.0) | 2 (1.7) |  |
   Stage IIIA | 0 (0.0) | 53 (46.1) |  |
   Stage IIIB | 4 (3.1) | 3 (2.6) |  |
   Stage IIIC | 0 (0.0) | 22 (19.1) |  |
Age at initial pathologic diagnosis (mean (sd)) | 54.87 (9.19) | 52.43 (9.08) | 0.039 |
Vital status follow up (%) | Â | Â | 0.142 |
   NA | 2 (1.7) | 3 (2.8) |  |
   Alive | 111 (91.7) | 89 (83.2) |  |
   Dead | 8 (6.6) | 15 (14.0) |  |
   OS time (mean (sd)) | 1108.70 (1069.91) | 1416.06 (1426.87) | 0.091 |
