Table 2 Genes with significantly different mutation rate between LN-negative and LN-positive groups.

From: Low mutation and neoantigen burden and fewer effector tumor infiltrating lymphocytes correlate with breast cancer metastasization to lymph nodes

Gene

LN-positive (n = 99)

LN-negative (n = 118)

p-value

DST

0

10

0.002187

PCNT

0

9

0.004294

LRP1B

1

11

0.00713

HERC2

0

8

0.008435

RB1

0

8

0.008435

ZDBF2

0

8

0.008435

PCDH15

0

7

0.01658

PREX2

0

7

0.01658

TNIK

0

7

0.01658

XIRP2

0

7

0.01658

ZNF536

0

7

0.01658

DNAH7

1

9

0.02326

VPS13C

1

9

0.02326

TP53

32

56

0.02681

MUC16

4

15

0.02957

BIRC6

0

6

0.03265

BRCA1

0

6

0.03265

CECR2

0

6

0.03265

CNTNAP5

0

6

0.03265

DUSP27

0

6

0.03265

PCDH19

0

6

0.03265

PDE4B

0

6

0.03265

RP1

0

6

0.03265

SI

0

6

0.03265

TPR

0

6

0.03265

TRPS1

0

6

0.03265

PLD5

4

0

0.04189