Figure 3 | Scientific Reports

Figure 3

From: Positively interacting strains that co-circulate within a network structured population induce cycling epidemics of Mycoplasma pneumoniae

Figure 3

Two examples of epidemic curve from LH samples under the situation of no interaction within the secondary infection (i.e., ν = μ = 1). Panel (a) degree of contact (κ) = 5.69, cross-immunity (ψ) = 0.415, infectious period (D) = 17.2 days and duration of immunity (d) = 9.2 years, inter-epidemic period (EpiT) = 4 years, the coefficient of variance of the incidence time series (CV) = 0.51; panel (b) κ = 3.34, ψ = 0.202, D = 37.7 days, d = 4.1 years, and EpiT = 4 years, CV = 0.93. The legend is provided in the title to each figure. It is obvious that the proportion of individuals that are simultaneously immune to both strains is kept low in the two examples. The proportion of individuals immune to one strain alone is temporally highly anti-correlated with the proportion of these immune to the other strain alone, with the correlation coefficient −95% and −84% for panel (a) and panel (b) respectively.

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