Figure 2
From: Systems Biology Approach to Identify Novel Genomic Determinants for Pancreatic Cancer Pathogenesis
Identification of dysregulated genes in tissue datasets. (a) Venn diagram of the common mRNAs in HC vs CP; HC vs PDAC and HC vs MPDAC comparisons. (b) Partitioning of samples on the basis of expression profile of genes using SOM clustering method. We identified two strikingly opposite expression patterns (black ellipses). ‘n’ represents the number of samples clustered. (c) Violin plots representing the two patterns observed in SOM partitioning. (d) Top 20 GO categories of DE mRNA common across all conditions (blue bar). (e) Top 20 Pathway categories of DE mRNA common in DE progressive mRNA in all conditions.
