Figure 3 | Scientific Reports

Figure 3

From: Patients with anti-Jo1 antibodies display a characteristic IgG Fc-glycan profile which is further enhanced in anti-Jo1 autoantibodies

Figure 3

3D-plot of the three factors (agalactosylation, bisection, and afucosylation) that best distinguished the anti-Jo1 specific IgG (red circles) and Jo1+ patients total IgG (black circles) from both total IgG from controls (blue circles), and from Jo1− patients (green circles). Thus, the anti-Jo1 specific IgG and the Jo1+ patients total IgG has 1) an increase in IgG1 agalactosylation (described by log(FA2_1/FA2_2) and 2) a decline in bisected forms (described by log Σ[B]) and 3) a decline in afucosylated forms (described by logΣ [aF]).

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