Figure 5

The Changes in ultrastructure of retinal nerve cells. (a) RGC in sham rats contained large and unbroken nuclei and intact nuclear membranes (thin short white arrow), and rich mitochondria (thin short black arrow) and endoplasmic reticulum (long white arrow). (b) RGC in BCCAO rats showed serious karyopyknosis, chromatic agglutination (thick short black arrow), decreased or swelling mitochondria (thin short black arrow) and vacuolization of endoplasmic reticulum (long black arrow), surrounded with a large number of proliferating microglial cells (thick short white arrow). (c) ONL cells in sham rats were neatly and tightly arranged, with unbroken nuclei (short white arrow). (d) ONL cells in BCCAO rats were with shrunken and invaginated nuclear membranes (short white arrow), and the chromatin was uneven density (short black arrow).