Table 2 Results of the multivariate logistic regression analysis for the association between hs-CRP and depression (PHQ-9 ≥ 10).

From: Sex Difference in the Association between High-sensitivity C-reactive Protein and Depression: The 2016 Korea National Health and Nutrition Examination Survey

 

Depression (PHQ-9 ≥ 10)

Men

Women

OR

95% CI

p-value

OR

95% CI

p-value

Serum hs-CRP

  Low: less than or equal to 3.0 mg/L

1.00

   

1.00

   

  High: above 3.0 mg/L

1.86

1.07

3.25

0.029

1.10

0.67

1.80

0.704

Age (years)

  20–29

1.00

   

1.00

   

  30–39

1.90

0.80

4.50

0.146

0.93

0.47

1.85

0.840

  40–49

1.34

0.52

3.44

0.547

0.33

0.15

0.74

0.007

  50–59

0.60

0.20

1.84

0.373

0.19

0.06

0.60

0.005

  60–69

0.75

0.24

2.41

0.633

0.15

0.04

0.50

0.002

  70–79

0.45

0.13

1.55

0.205

0.13

0.04

0.46

0.001

  ≥80

0.40

0.08

1.92

0.250

0.06

0.01

0.24

<0.0001

Educational attainment

  Elementary school and below

1.00

   

1.00

   

  Middle school

0.51

0.23

1.15

0.105

0.90

0.57

1.43

0.654

  High school

0.51

0.26

1.01

0.055

0.50

0.30

0.83

0.007

  University or above

0.48

0.23

1.02

0.055

0.46

0.26

0.83

0.009

Equalized household income

  Quartile 1 (low)

1.00

   

1.00

   

  Quartile 2

0.47

0.27

0.83

0.009

0.52

0.36

0.77

0.001

  Quartile 3

0.26

0.13

0.51

<0.0001

0.54

0.36

0.82

0.004

  Quartile 4 (high)

0.20

0.09

0.41

<0.0001

0.23

0.13

0.40

<0.0001

Marital status

  Married

1.00

   

1.00

   

  Separated/divorced/widowed

3.55

1.96

6.41

<0.0001

1.70

1.19

2.44

0.003

  Never married

2.52

1.33

4.79

0.005

1.51

0.81

2.84

0.196

Alcohol use status

  No

1.00

   

1.00

   

  Yes

1.21

0.74

1.98

0.460

0.94

0.69

1.28

0.673

Smoking status

  Non-smoker

1.00

   

1.00

   

  Smoker

2.16

1.38

3.38

0.001

4.04

2.51

6.49

<0.0001

Chronic medical disease

  None

1.00

   

1.00

   

  One

1.68

0.90

3.12

0.104

2.04

1.34

3.10

0.001

  Two or more

2.78

1.50

5.18

0.001

2.45

1.58

3.80

<0.0001

Residential area

  Urban

1.00

   

1.00

   

  Rural

1.07

0.68

1.68

0.773

1.12

0.84

1.50

0.437

BMI

  Underweight

1.93

0.75

4.97

0.170

0.72

0.32

1.62

0.429

  Normal weight

1.00

   

1.00

   

  Overweight

0.82

0.51

1.33

0.427

1.08

0.79

1.49

0.628

  Obesity

0.73

0.29

1.82

0.494

0.90

0.50

1.63

0.735

Menopause (females only)

  No

    

1.00

   

  Yes

    

2.12

0.84

5.34

0.110

  1. PHQ-9, patient health questionnaire-9; hs-CRP, high-sensitivity C-reactive protein; BMI, body mass index; OR, odds ratio; CI, confidence interval.