Table 4 Subgroup analysis of the association between hs-CRP and depression (PHQ-9 ≥ 10) stratified by sociodemographic variables in women.

From: Sex Difference in the Association between High-sensitivity C-reactive Protein and Depression: The 2016 Korea National Health and Nutrition Examination Survey

Women

Low hs-CRP

(≤3.0 mg/L)

High hs-CRP

(>3.0 mg/L)

OR

OR

95% CI

p-value

Age (years)

  20–29

1.00

1.34

0.29

6.15

0.704

  30–39

1.00

1.39

0.47

4.10

0.554

  40–49

1.00

4.50

1.42

14.29

0.011

  50–59

1.00

1.26

0.37

4.28

0.717

  60–69

1.00

0.48

0.11

2.05

0.320

  70–79

1.00

1.04

0.42

2.59

0.938

  ≥80

1.00

2.19

0.41

11.79

0.361

Educational attainment

  Elementary school and below

1.00

0.98

0.49

1.97

0.957

  Middle school

1.00

2.86

0.98

8.33

0.055

  High school

1.00

1.36

0.52

3.52

0.532

  University or above

1.00

1.05

0.32

3.46

0.942

Equalized household income

  Quartile 1 (low)

1.00

1.06

0.53

2.11

0.864

  Quartile 2

1.00

1.08

0.42

2.81

0.874

  Quartile 3

1.00

2.12

0.92

4.93

0.080

  Quartile 4 (high)

1.00

<0.001

<0.001

>999.99

0.973

Marital status

  Married

1.00

1.44

0.78

2.68

0.247

  Separated/divorced/widowed

1.00

0.92

0.40

2.12

0.850

  Never married

1.00

2.34

0.75

7.34

0.143

Alcohol use status

  No

1.00

1.47

0.77

2.80

0.238

  Yes

1.00

1.24

0.65

2.36

0.515

Smoking status

  Non-smoker

1.00

1.00

0.58

1.72

0.985

  Smoker

1.00

5.77

1.72

19.34

0.005

Chronic medical disease

  None

1.00

1.48

0.75

2.90

0.259

  One

1.00

2.01

0.92

4.37

0.078

  Two or more

1.00

0.56

0.20

1.62

0.286

Residential area

  Urban

1.00

1.43

0.70

2.95

0.331

  Rural

1.00

1.34

0.75

2.39

0.329

BMI

  Underweight

1.00

<0.001

<0.001

>999.99

0.981

  Normal weight

1.00

1.12

0.53

2.34

0.775

  Overweight

1.00

1.10

0.51

2.37

0.818

  Obesity

1.00

2.28

0.81

6.43

0.120

Menopause (females only)

  No

1.00

1.64

0.77

3.50

0.203

  Yes

1.00

1.16

0.66

2.03

0.612

  1. PHQ-9, patient health questionnaire-9; hs-CRP, high-sensitivity C-reactive protein; BMI, body mass index; OR, odds ratio; CI, confidence interval.