Figure 2
Adjusted HRs for hospital-reported NAFLD by usual level of (a) BMI and (b) WC, with the right panel showing the age and sex-specific HRs per 1-SD higher usual BMI and WC. In the left panel, BMI is classified as <20.0, 20.0 to <22.5, 22.5 to <25.0, 25.0 to <27.5, 27.5 to <30.0, and ≥30.0 kg/m2. WC is classified by sextiles as <70.7, 70.7–75.2 (reference), 75.3–79.6, 79.7–84.0, 84.1–89.9, and ≥90.0 cm. Hazard ratios (HRs) are plotted against the mean level in each group. Log-scale is used for the y-axis. The squares represent HRs, and the vertical lines represent 95% CIs. Numerical values above the 95% CI represent the hazard ratio and values beneath the 95% CI represent the number of cases of NAFLD in each group. In the right panel, boxes represent sex-specific estimates by age-at-risk categories. Diamonds represent summary HRs for each age-at-risk category and the overall HR. Estimates and 95% CI of the summary HRs are in bold. In both panels, the sizes of the boxes are proportional to the inverse of the variance of the log hazard ratios. The analyses are stratified by sex, region, and HBsAg, and adjusted for age at baseline, education, smoking, alcohol, and total physical activity. SD was 3.3 kg/m2 for BMI and 9.8 cm for WC. HR per 1-SD was corrected for regression dilution (regression dilution ratio: BMI = 0.93, WC = 0.84).
