Figure 3
From: Astrocytoma progression scoring system based on the WHO 2016 criteria
Different mutation and copy number variation patterns of the AP score. (a) Summary of well-known individual regulators of glioma from 460 samples from the training cohort. Columns are sorted by samples with increasing AP scores. Top histogram, the sum of mutations in each sample category is indicated by the legend; Right histogram, the sum of mutations in each gene is indicated by the legend. (b) The overall copy number variation (CNV) profile in order of increasing AP score. (c,d) A distinct CNV and recurrent mutation profile is observed between astrocytomas with low and high AP scores. *P < 0.05; **P < 0.01; ***P < 0.001.
