Figure 4 | Scientific Reports

Figure 4

From: Toxicity and possible mechanisms of action of honokiol from Magnolia denudata seeds against four mosquito species

Figure 4

Effects on cyclic AMP levels. A whole-body homogenate from third-instar Aedes aegypti larvae was tested for adenylate cyclase activity, as described in the Methods section, in the presence of honokiol (100 µM) and magnolol (100 µM). The effects of the neolignans on cyclic AMP (cAMP) levels of the homogenate were compared with those of octopamine (100 µM) alone. Data were expressed as nmol/4.12 μg protein. Each bar represents the mean ± standard error of duplicate samples from three independent experiments (***P < 0.001; ns, no significant difference, using Bonferroni’s multiple comparisons test).

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