Figure 2 | Scientific Reports

Figure 2

From: Expression of NOTCH3 exon 16 differentiates Diffuse Large B-cell Lymphoma into molecular subtypes and is associated with prognosis

Figure 2

Exon specific expression of NOTCH3. RMA normalized exon specific expression assessed by HuEx. 1.0 array with focus on exon 15–18 of the NOTCH3 gene, as an alternatively spliced transcript missing exon 16 was identified, in DLBCL patients classified as (A) ABC/GCB subclasses, (B) BAGS subtypes, and (C) GCB-centroblast and GCB-centrocyte. Data points represent the mean probe set expression in the respective exons for each molecular subtype of DLBCL. ABC: activated B-cells, GCB: germinal center B-cells, CB: centroblast, CC: centrocyte, M: memory, and PB: plasmablast. RMA: Robust Multichip Average normalized.

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