Figure 5

The NOTCH3 −exon 16 transcript associate with REGS vincristine subtypes and trends to associate with OS. Subtype association with NOTCH3 −exon 16 expression in vincristine response subtypes of (A) the entire cohort and (B,C) within ABC and GCB classified patients. Pink and green data points represent centrocyte and centroblast classified patients, respectively. (D) Kaplan-Meier estimates of NOTCH3 −exon 16 expression and OS in the entire DLBCL cohort (n = 60), (E) within the ABC subclass (n = 26), and (F) within the GCB subclass (n = 26). **p < 0.001. ABC: activated B-cells, GCB: germinal B-cells.