Figure 2 | Scientific Reports

Figure 2

From: Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine

Figure 2

Quality of the pre-existing influenza-specific cytokine profile remains unchanged following TIV vaccination. (A,B) Distribution of positive cytokine responses from subjects before and after vaccination with trivalent influenza vaccine (n = 10). PBMCs were cultured with (A) PMA and ionomycin, and (B) the TIV vaccine and peptide pools specific for A/California/7/2009 HA, MP1 and NP proteins. Levels of the indicated cytokines were measured in the cell culture supernatants after eight days incubation. The size of the charts is proportional to the magnitude of the response (number of positive responses in all subjects for that visit is indicated for each chart; maximum of 150). Labels “Pre”, “Post1” and “Post2”, refer to Day 0, Day 21 and Day 42 post primary vaccination respectively.

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