Table 1 Quantification of PI resistance.

From: Targeting HIV-1 Protease Autoprocessing for High-throughput Drug Discovery and Drug Resistance Assessment

Group and patient ID

darunavir

indinavir

aFold change by PhenoSenseĀ®

bFold change by AlphaLISA

aFold change by PhenoSenseĀ®

bFold change by AlphaLISA

1319

0.4

1.7

38

ā‰„100

634

39

43

ā‰„200

ā‰„200

6585

112

52

88

~80

14311

>200

>1000

48

>700

38129

>200

>1000

24

>700

  1. aPI resistance values reported previously51.
  2. bPI resistance values determined by AlphaLISA analysis in this report from three independent experiments.
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