Table 2 Descriptive/demographic statistics for individuals included in final linear regression models (n = 75).

From: Polygenic impact of common genetic risk loci for Alzheimer’s disease on cerebral blood flow in young individuals

Gender

APOE ɛ4 (−) n = 54

APOE ɛ4 (+) n = 21

P

M = 19/F = 35

M = 9/F = 12

X2 = 0.12

0.726

Mean

SD

Mean

SD

 

Age

23.759

3.192

23.952

3.170

0.814

GMV

0.767

0.011

0.768

0.011

0.719

AD-PRS

−0.075

0.935

0.192

1.154

0.351

SoP

68.764

23.639

76.042

19.612

0.185

AV

44.214

26.689

51.118

22.990

0.276

WM

56.411

21.998

58.161

23.945

0.775

VrblLrng

51.480

28.071

47.137

29.272

0.566

VisLrng

66.795

25.647

62.667

27.922

0.563

RPS

54.906

28.815

62.205

24.900

0.287

SC

45.295

25.777

47.147

30.897

0.810

Comp

59.971

23.479

63.183

18.739

0.543

  1. X2 = chi squared test for gender. All other demographics were tested via two-sample t-test. SD = standard deviation. GMV = grey matter volume; AD-PRS = Alzheimer’s disease polygenic risk score (z-scores). SoP = Speed of Processing; AV = Attention Vigilance; WM = Working Memory; VrblLrng = Verbal Learning; VisLrng = Visual Learning; RPS = Reasoning and Problem Solving; SC = Social Cognition; Comp = Composite Cognition Score.
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