Figure 2 | Scientific Reports

Figure 2

From: Evaluating analgesic efficacy and administration route following craniotomy in mice using the grimace scale

Figure 2

Time course postsurgery for injected drugs. Mean difference scores are shown for carprofen (10 and 25 mg/kg), meloxicam (2 and 5 mg/kg) and buprenorphine (0.1 mg/kg) compared with saline (control) for pooled sexes (A), male mice (B), and female mice (C). Each drug has been color-coded as indicated by the legend and significance at each time point was determined by comparing with saline control. The color of the asterisks corresponds to the appropriate drug. *p < 0.05; **p < 0.01, ***p < 0.001.

Back to article page