Figure 4 | Scientific Reports

Figure 4

From: Evaluating analgesic efficacy and administration route following craniotomy in mice using the grimace scale

Figure 4

Comparison of AUC scores for control, carprofen (10 and 25 mg/kg), meloxicam (2 and 5 mg/kg) and buprenorphine (0.1 mg/kg) over the entire 72 h postoperative period compared across administration route (injected vs. water supply). Pooled sexes (A), male mice (B) and female mice (C) are shown. Comparisons were conducted between administration routes for each panel, with lower AUC scores for female mice administered carprofen through the water supply. *p < 0.05, **p < 0.01.

Back to article page