Table 1 Estimated average drug dose (mg/kg) ingested compared to injected drug dose using a one-sample t-test.

From: Evaluating analgesic efficacy and administration route following craniotomy in mice using the grimace scale

Drug

Injected Dose (mg/kg)

Calculated Oral Dose (mg/kg)

One sample t-test

Carprofen

10 (n = 8 M, 8 F) 25 (n = 8 M, 8 F)

11.46 ± 1.09 (n = 8 M, 8 F) 22.92 ± 1.99 (n = 8 M, 8 F)

t7 = 1.35, p = 0.22 t7 = −1.05, p = 0.33

Meloxicam

2 (n = 8 M, 8 F) 5 (n = 8 M, 7 F)

1.84 ± 0.08 (n = 8 M, 8 F) 6.98 ± 1.00 (n = 8 M, 8 F)

t7 = −1.73, p = 0.13 t7 = 1.96, p = 0.09

Buprenorphine

0.1 (n = 8 M, 8 F)

0.11 ± 0.008 (n = 8 M, 8 F)

t7 = 1.25, p = 0.25

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