Figure 1 | Scientific Reports

Figure 1

From: Delivery of mRNA to platelets using lipid nanoparticles

Figure 1

mRNA delivered by icLNPs and cLNPs is internalized. (a) Confocal immunofluorescence microscopy of platelets (red) transfected with LNPs containing biotin-labelled RNA (green). Representative images from 4 separate donors are shown. All scale bars indicate 2 µm. (b) Quantifying biotin-labelled RNA inside the platelets from images in panel A (n = 4). (c) The amount of Cy5-positive platelets transfected with Cy5-mRNA was quantified by flow cytometry (n = 5). Error bars represent SEMs. **P < 0.01, ***P < 0.001.

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