Figure 7
From: Delivery of mRNA to platelets using lipid nanoparticles
mRNA delivered by LNPs is released in platelet MPs. MPs were isolated from platelets prepared with LNPs and resuspended in either Tyrode’s buffer, with or without activation, or in plasma without activation. (a) The number of Cy5-positive and Cy5-negative MPs from 1 × 108 platelets, quantified using flow cytometry (n = 6). (b) The amount of FLuc mRNA in all MPs from 1 × 108 platelets, quantified by qPCR (n = 7). Error bars represent SEMs. *P < 0.05, **P < 0.01.
