Figure 4 | Scientific Reports

Figure 4

From: Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule

Figure 4

Effects of butyrate-related molecules on histone acetylation in L6 myotubes. (A) L6 myotubes were incubated for 18 hours with NaBut, the indicated butyrate-related molecules or TSA. Acid-extracted histones were immunoblotted with antibodies anti H2A.ZAc, anti H3K9/14Ac, anti H3K9Ac, anti H3K9Me2 or stained with coomassie blue as indicated. Signal quantification from representative western blots, relative to the coomassie blue staining signal, is shown next to each immunoblot. (B) Chemical formulas of NaBut and butyrate related molecules.

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