Figure 6 | Scientific Reports

Figure 6

From: Prominent action of butyrate over β-hydroxybutyrate as histone deacetylase inhibitor, transcriptional modulator and anti-inflammatory molecule

Figure 6

Effects of NaBut and NaR-βOHB (R-βOHB in graphs) on transcription of genes involved in insulin action. Quantification of the mRNA levels by RT qPCR for Glut4, HK2, IRS1, Gs, Gsk-3β and Hmgcs1 in L6 myotubes treated for 24 h with 5 mM NaBut (grey bars) or 20 mM NaR-βOHB (black bars). Gene expressions are normalized to the Hprt1 housekeeping gene. Error bars represent the mean ± SEM from 3 independent experiments. (*p < 0.05, versus Ctrl group using one-way ANOVA).

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