Table 1 Significant DEGs with opposite and same regulation pattern between DA and non-DA neuron results.

From: Comparison between dopaminergic and non-dopaminergic neurons in the VTA following chronic nicotine exposure during pregnancy

Gene Symbol

Entrez ID

DA

Non-DA

DA logFC

DA adj p val

Non-DA logFC

Non-DA adj p val

Opposite Regulation

Pfkp

60416

−1

1

−2.065

3.858 × 10−4

1.127

4.981 × 10−4

Cstf2

683927

−1

1

−2.378

4.238 × 10−4

1.77

1.723 × 10−4

LOC102546798

102546798

−1

1

−1.667

4.657 × 10−4

1.464

9.518 × 10−5

LOC102549148

102549148

−1

1

−1.603

8.797 × 10−3

1.224

6.365 × 10−4

LOC103690149

103690149

−1

1

−1.321

1.464 × 10−3

1.157

7.029 × 10−4

LOC102547481

102547481

−1

1

−1.978

1.539 × 10−3

2.998

7.694 × 10−5

Chd2

308738

−1

1

−1.515

1.550 × 10−3

1.358

8.841 × 10−4

Abcg4

300664

−1

1

−1.386

1.587 × 10−3

1.266

8.357 × 10−4

Ndrg4

64457

−1

1

−1.322

2.772 × 10−3

1.549

5.995 × 10−4

Zmym3

317260

−1

1

−1.708

3.267 × 10−3

1.988

8.149 × 10−4

Tra2a

500116

−1

1

−1.223

3.896 × 10−3

1.798

3.416 × 10−4

Nktr

100364165

−1

1

−1.156

8.475 × 10−3

1.868

6.782 × 10−4

Nepn

309775

1

−1

1.638

8.145 × 10−4

−1.106

8.719 × 10−4

Sept11

305227

1

−1

1.020

1.464 × 10−3

−1.642

4.950 × 10−5

Same Regulation

Pgap3

688174

−1

−1

−3.213

6.970 × 10−4

−1.266

7.735 × 10−3

Plxnd1

312652

−1

−1

−2.103

9.318 × 10−4

−1.373

1.434 × 10−3

Osbp2

305475

−1

−1

−1.142

2.106 × 10−3

−1.361

3.640 × 10−4

Nefh

24587

−1

−1

−1.759

3.474 × 10−3

−2.073

8.666 × 10−4

RatNP-3b

498659

−1

−1

−1.96

4.512 × 10−3

−3.364

2.043 × 10−4

LOC102553761

102553761

−1

−1

−2.092

5.354 × 10−3

−2.876

7.832 × 10−4

Ids

363513

1

1

1.005

7.766 × 10−3

2.132

1.628 × 10−4

  1. Forty-five and 33 DEGs are shown with opposite and same regulation pattern, respectively. Regulation is noted as 1 for upregulation and −1 for downregulation. Log fold-change and BH-corrected p-value are listed.
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