Figure 2

Difference from placebo (Day –1 of respective treatment) in mean change from baseline in QTcF on Day 3. Data are presented as mean and 90% confidence interval. The dotted horizontal line corresponds to the 10 ms threshold. DHA-PQP = dihydroartemisinin-piperaquine phosphate. Square = DHA-PQP low caloric breakfast; triangle = DHA-PQP high caloric breakfast; filled circle = DHA-PQP fasted; open circle = artemether-lumefantrine.