Figure 3

Effect of rh-BDNF on lysis of fibrin clot in healthy subjects’ plasma. Recombinant BDNF (rh-BDNF; 60, 120 pg/ml) or BSA (1 mg/ml: control) were added to five plasma pools from healthy subjects before induction of coagulation with thrombin and tPA, consequently polymerization of clot were analyzed. (a) Representative turbidity curves monitored by spectrophotometric method every 23 sec (A350 nm at 37 °C), (b) % of Lysis at 60 minutes and (c) Lysis time. All samples were performed in triplicate. Data are expressed as mean ± SEM; n = 5 different pools.