Figure 4

rh-BDNF influences thrombin (TCT) and e) reptilase (RCT) clotting time in healthy subjects’ plasma. Recombinant BDNF (rh-BDNF; 60, 120 pg/ml) or BSA (1 mg/ml: control) were added to plasma pools from healthy subjects, then (a) thrombin (TCT) and (b) reptilase (RCT) clotting time were measured. All samples were performed in triplicate. Data are expressed as mean ± SEM; horizontal bars indicate variation of BDNF levels measured in plasma pools analyzed; n = 5 different pools. *p < 0.05 and **p < 0.01.