Table 1 Eco- and cytotoxicity battery assay of PSC and its degradation products.
Eco-/Cytotoxicity | Media/Organ | Assays | Pb | Concentrations (mg/L, Control = 0) | EC50 (Interval of Confidence) | ||||
|---|---|---|---|---|---|---|---|---|---|
0.1 | 1 | 10 | 100 | ||||||
Eco toxicity | Aquatic Toxicity | Water column | Daphnia Immobilization (48 h) | Pb2+ | 30.0 ± 23.8 | 100** | 100** | 100** | 0.13 (−0.21 ~ 0.48) |
PbI2 | 10.0 ± 5.8 | 55.0 ± 12.6 | 77.5 ± 22.5* | 100** | 1.04 (−0.10 ~ 2.18) | ||||
PbO | 0.3 ± 0.3 | 35.0 ± 23.6 | 85.0 ± 15.0* | 73.3 ± 11.5* | 2.06 (−0.04 ~ 4.15) | ||||
PSC | 10.0 ± 10.0 | 30.0 ± 23.8 | 95.0 ± 5.0* | 100** | 1.71 (0.54 ~ 2.89) | ||||
Zebrafish Embryo Coagulation (96 h) | Pb2+ | 0 | 5.9 ± 2.9 | 100** | 100** | ||||
PbI2 | 0 | 0.6 | 10.4 ± 4.4 | 6.1 ± 4.1 | |||||
PbO | 0 | 0.6 | 7.0 ± 2.5 | 7.0 ± 3.1 | |||||
PSC | 0 | 0 | 5.1 ± 3.0 | 98.8 ± 1.2** | |||||
Sediment | Chironomus Mortality (48 h) | Pb2+ | 0 | 0 | 100** | 100** | |||
PbI2 | 3.3 ± 3.3 | 20 ± 10 | 13 ± 3.3 | 6.7 ± 6.7 | |||||
PbO | 0 | 16.7 ± 3.3* | 10.0 ± 5.8 | 23.3 ± 8.8 | |||||
PSC | 3.3 ± 3.3 | 6.7 ± 6.7 | 3.3 ± 3.3 | 10.0 ± 5.8 | |||||
Soil Toxicity | Soil | C. elegans Growth inhibition (48 h) | Pb2+ | 14.1 ± 0.7* | 19.8 ± 1.2* | 100** | 100** | ||
PbI2 | 7.4 ± 1.1* | 5.1 ± 2.9 | 8.1 ± 4.1 | 18.2 ± 1.9* | |||||
PbO | 11.6 ± 1.3 | 20.0 ± 2.1** | 29.6 ± 0.7** | 17.2 ± 1.4** | |||||
PSC | 13.2 ± 2.0** | 17.4 ± 3.3** | 17.7 ± 2.9** | 18.5 ± 0.8** | |||||
Human toxicity | Cytotoxicity | Lung | Beas2B cell death (24 h) | Pb2+ | 8.4 ± 7.3 | 3.8 ± 1.3 | 17.8 ± 8.2 | 53.4 ± 19.9 | |
PbI2 | 6.8 ± 4.7 | 24.8 ± 12.4 | 25.9 ± 7.6* | 27.5 ± 8.6* | |||||
PbO | 0.7 ± 0.7 | 3.8 ± 0.9* | 26.3 ± 10.7 | 20.4 ± 8.5 | |||||
PSC | 13.4 ± 6.8 | 23 ± 8.2* | 33.9 ± 6.7* | 38.9 ± 4.8** | |||||
Liver | HepG2 cell death (24 h) | Pb2+ | 5.2 ± 1.5* | 11.5 ± 1.6** | 23 ± 2.0** | 29.6 ± 3.1** | |||
PbI2 | 8.8 ± 2.3* | 6 ± 3.1 | 11.9 ± 2.5* | 8.9 ± 2.3* | |||||
PbO | 13.4 ± 2.8* | 12.2 ± 2.7* | 15.1 ± 2.4** | 10.7 ± 1.0** | |||||
PSC | 3.1 ± 1.3 | 7.1 ± 0.6** | 21.8 ± 5.2* | 19.7 ± 3.1** | |||||