Figure 2
Augmentation of ms-TRFS derived data on the Surgeon console during oral cavity surgery. (a) The conventional three-dimensional visualization from the endoscope. The 445 nm aiming beam used to identify the location probed by ms-TRFS is visible at the distal end of the tool. The panels labeled with (1) and (2) correspond to the lifetime maps that can be visualized and the linear representation of lifetime values, respectively. (b) The white-light image augmented with lifetime values from channel 1 of the instrument. (c) The transient signals over the four channels of the system for two locations (pixels) measured. The fluorescence pulse transients from all four channels are simultaneously acquired and analyzed to all relevant emission parameters (i.e. integrated intensity, lifetime, and 12 Laguerre coefficients). (d) Matrix of the distribution maps for the autofluorescence parameters. Note, each of these maps can be displayed/augmented in real-time during the scanning procedure if needed.
