Figure 2
The prognostic value of PKD2 and its relationship with E-cadherin by IHC. (A) Representative images of different expressions of PKD2 and E-cadherin. a. high expression of PKD2 (400×); b low expression of PKD2 (400×); c. negative expression of PKD2 for control group (400×); d high expression of E-cadherin (400×); e low expression of E-cadherin (400×); f negative expression of E-cadherin for control group (400×). The red arrows indicated PDK2-expressing cells while the yellow arrows indicated E cadherin-expressing cells. (B) PKD2 was negatively related with E-cadherin (p = 0.021). (C,D) Kaplan-Meier curves for PKD2 expression and OS, PFS. High expression of PKD2 was associated with shorter OS (p = 0.015) and PFS (p = 0.006). (E,F) Kaplan-Meier curves for E-cadherin expression and OS, PFS. High expression of E-cadherin was related to positive prognosis of patients with lung adenocarcinoma (OS: p = 0.003; PFS: p = 0.003).
