Table 1 CRABP2 mRNA levels in sensitive and resistant lines of seven chemotherapeutics using data from Barrentina.
From: Crabp2 Promotes Metastasis of Lung Cancer Cells via HuR and Integrin β1/FAK/ERK Signaling
Barrentina | n | CRABP2 expression | p a | |
|---|---|---|---|---|
Low | High | |||
CDK Inhibitor PD-0332991 | ||||
Sensitive | 13 | 11 | 2 | 0.0110 |
Resistant | 362 | 175 | 187 | |
Irinotecan | ||||
Sensitive | 71 | 52 | 19 | 0.0002 |
Resistant | 84 | 36 | 48 | |
MEK Inhibitor PD0325901 | ||||
Sensitive | 75 | 51 | 24 | 0.0003 |
Resistant | 311 | 138 | 173 | |
HDAC Inhibitor Panobinostat | ||||
Sensitive | 86 | 65 | 21 | <0.0001 |
Resistant | 164 | 67 | 97 | |
Selumetinib | ||||
Sensitive | 37 | 28 | 9 | 0.0002 |
Resistant | 367 | 160 | 207 | |
Sorafenib | ||||
Sensitive | 9 | 8 | 1 | 0.0155 |
Resistant | 408 | 190 | 218 | |
Topotecan | ||||
Sensitive | 154 | 95 | 59 | 0.0002 |
Resistant | 124 | 48 | 76 | |