Table 1 Effect of TL and SKF on CD38 expression in leukemic blast cell lines.

From: Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation

 

% CD38 (K562)

% CD38(U937)

% CD38(THP-1)

Control

8.22

48.2

99.6

VSKF

11.4

59.2

99.5

SKF50

3.3

25.2

90.1

SKF100

0.5

13.2

80.4

VTL

6.5

52.3

99.9

TL200

2.8

38.7

99.8

TL500

3.1

10.5

99.9

  1. Leukemia cell lines were treated with TL or SKF for 48 h (K562 and U937) or 96 h (THP-1), immunostained with fluorescently labeled anti-CD38 antibody, and analyzed by flow cytometry to detect surface marker CD38. Only live cell populations were analyzed in each condition. Data (expressed as percentage of cells expressing CD38) were computed from a representative experiment.
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