Figure 4 | Scientific Reports

Figure 4

From: X-ray structure of Fasciola hepatica Sigma class glutathione transferase 1 reveals a disulfide bond to support stability in gastro-intestinal environment

Figure 4

The GSSG complex interactions in the active site of FhGST-S1. (a) Electron-density maps of the active site of the FhGST-S1 GSSG complex. The 2Fo - Fc map (blue) is contoured at 1.0 σ and the Fo - Fc map is contoured at 3.0 σ (green) and −3.0 σ (red). The GSSG molecule and neighbouring residues are shown as stick models and the solvent molecules are shown as red stars. (b) The key interactions of the GSSG molecule in the FhGST-S1 active site shown using a LIGPLOT+ diagram35.

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