Figure 3 | Scientific Reports

Figure 3

From: Identification of Key Signaling Pathways Orchestrating Substrate Topography Directed Osteogenic Differentiation Through High-Throughput siRNA Screening

Figure 3

Summary of the filtered genes are shown in the diagram for each library (kinase and phosphatase). The unbiased selection criteria used in the statistical analysis step allowed distinguishing of upregulating, downregulating and no change targets for each topography. There were a significant number of intersecting genes in both smooth and fiber topography categories. A two sample t-test statistical analysis was performed to distinguish the different genes in this category.

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