Figure 5
Differential pattern of CNAs in actionable genes in the TCGA and GENIE cohort across NSCLC and colorectal cancer. (a) Bars depict the proportion of tumors with CNAs in potentially actionable genes altered in NSCLC samples. (b) Bars depict the proportion of tumors with CNAs in potentially actionable genes altered in colorectal cancer samples. The percentage of tumors with hemizygous deletion (grey), homozygous deletion (yellow), low-level gain (blue) and high-level amplification (red) are shown. The Fisher’s exact test was used to determine whether the frequencies of CNAs are different in potentially actionable genes between TCGA and GENIE datasets analyzed by the array and NGS-based technologies.
