Figure 1 | Scientific Reports

Figure 1

From: The Placental Transcriptome in Late Gestational Hypoxia Resulting in Murine Intrauterine Growth Restriction Parallels Increased Risk of Adult Cardiometabolic Disease

Figure 1

Birthweights, litter sizes, and gestational length of late gestational-room air (LG-RA) and late-gestational hypoxia (LG-H) groups. (A) LG-H exposure results in a ~10% decrease in birthweight compared to LG-RA. Data are represented in graphs as means ± SD. The asterisk indicates a significant difference between LG-H (squares) and LG-RA (circles) groups (p = 0.002 by Student’s t-test). (B) LG-H exposure results in a ~30–40% reduction in litter sizes compared to LG-RA when considering all pups delivered (viable and non-viable) (p = 0.038). Data are represented in graphs as median with 95% confidence intervals. Asterisks indicate a significant difference between indicated LG-H group compared to LG-RA by Mann-Whitney testing. (C) LG-H exposure results in a ~50% reduction in litter sizes compared to LG-RA when considering only viable pups (p = 0.005). Data are represented in graphs as median with 95% confidence intervals. Asterisks indicate a significant difference between indicated LG-H group compared to LG-RA by Mann-Whitney testing. (D) There is no difference in gestational length between LG-RA and LG-H groups (p = 0.21 by Mann-Whitney test). Data are represented in graphs as median with 95% confidence intervals.

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