Figure 2 | Scientific Reports

Figure 2

From: Activation of Toll-like receptor 2 induces B1 and B2 kinin receptors in human gingival fibroblasts and in mouse gingiva

Figure 2

P. gingivalis LPS and the TLR2 agonist Pam2CSK4 increase the expression of B1 and B2 kinin transcripts in human gingival fibroblasts from different individuals. BDKRB1 (A) and BDKRB2 (B) were up-regulated after 6 h of exposure to P. gingivalis LPS (1 μg/mL) or Pam2CSK4 (50 ng/mL) in cells isolated from five individuals. Each bar represents the average of 3 wells/experimental group and SEM is given as vertical bars. *** and *** indicate significant difference to untreated control cells, P < 0.05, P < 0.01 and P < 0.001 respectively. Statistical significance was determined using one-way analysis of variance (ANOVA), with Levene’s homogeneity test and Dunnet’s T3 post hoc test.

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