Figure 2

Effects of zinc- and copper-containing welding fumes on cytokine release after whole blood incubation for 24 hours with four concentrations (0.1 µg/ml, 1 µg/ml, 10 µg/ml, 100 µg/ml). Incubation with 10 ng/ml LPS was conducted as positive control (LPS). The determined levels in pg/ml were divided by the mean level of the corresponding control. The dotted line indicates the corresponding control. All data are shown as mean ± SEM, (n = 7). (A) IL-13 levels, (B) IL-10 levels, (C) IL-4 levels, (D) IFNγ levels (E) IL-2 levels, (F) IL-12p70 levels. §p < 0.05, §§p < 0.01, §§§p < 0.001 for comparisons with the control. **p < 0.01 for comparison of differences within the welding fume concentrations.