Table 1 List of top twenty most differentially expressed genes between 800 µM MGO and Control (p < 0.05, fold change ≥ ±1.5).
Gene symbol | Gene name | Fold change | p-value |
|---|---|---|---|
800 µM MGO × Control: Up-regulated | |||
HO-1 | heme oxygenase 1 | 3.79 | 9.63E-5 |
PSAT1 | phosphoserine aminotransferase 1 | 3.55 | 5.93E-4 |
DKK1 | dickkopf WNT signaling pathway inhibitor | 3.49 | 5.40E-5 |
VTRNA1-3 | vault RNA 1-3 | 3.28 | 0.00620 |
PTGS2 | prostaglandin-endoperoxide synthase 2 | 3.27 | 0.00068 |
LPXN | leupaxin | 3.19 | 0.00012 |
SERPINB2 | plasminogen activator inhibitor 2 | 3.17 | 0.00420 |
ATP1B1 | ATPase Na+/K+ transporting subunit beta 1 | 3.14 | 2.90E-5 |
MARCH4 | membrane associated ring-CH-type finger 4 | 3.12 | 5.04E-5 |
IGFBP3 | insulin like growth factor binding protein 3 | 3.07 | 0.00018 |
800 µM MGO × Control: Down-regulated | |||
TOP2A | topoisomerase (DNA) II alpha | −13.88 | 0.00045 |
ASPM | abnormal spindle microtubule assembly | −13.30 | 0.00030 |
KIF20A | kinesin family member 20a | −10.96 | 9.58E-5 |
MKI67 | marker of proliferation Ki-67 | −10.92 | 0.00061 |
FABP4 | fatty acid binding protein 4, adipocyte | −9.85 | 0.00062 |
BUB1 | BUB1 mitotic checkpoint serine/threonine | −9.76 | 0.00016 |
TTK | TTK protein kinase | −8.74 | 0.00039 |
CASC 5 | cancer susceptibility candidate 5 | −8.72 | 0.00014 |
CCNA2 | cyclin A2 | −8.67 | 0.00085 |
DLGAP5 | DLG Associated Protein 5 | −8.38 | 0.00045 |
