Figure 2
From: micro-RNAs dependent regulation of DNMT and HIF1α gene expression in thrombotic disorders
Overrepresentation of Gene Ontology categories in Biological Networks identified from the list of target genes of shared miRNAs between HIF and DNMT family. (A) Enrichment network of shared DEGs based on biological processes. Significantly overrepresented biological processes based on GO terms were visualized in Cytoscape. The size of a node is proportional to the number of targets in the GO category. The color represents enrichment significance— the deeper the color on a color scale, the higher the enrichment significance. P-values were adjusted using a Benjamini and Hochberg False Discovery Rate (FDR) correction. (B) Table showing top five GO terms associated with the target genes. Overlap: indicates the number of hits from the meta-analysis compared to each curated gene set library; GO: gene ontology biological process.
