Table 2 Characteristics of individual studies included in the miRNA meta-analysis of hypoxic exposure.

From: micro-RNAs dependent regulation of DNMT and HIF1α gene expression in thrombotic disorders

S. No.

GEO accession no.

Platform of dataset

Samples(Ctl/exp)

No. of miRNAs

Organism

Sample source

Platform

Model of generating expression summaries

Reference

1

[GSE47532]

GPL8227

(n = 11) 3/8

820

Homo Sapiens

breast cancer cell line MCF-7

Agilent-019118 Human miRNA Microarray 2.0 G4470B

log2 transformed and quantile normalized

73

2

[GSE60432 12 h]

GPL14550

(n = 08) 4/4

851

Homo Sapiens

human placental trophoblast cells

Agilent-028004 SurePrint G3 Human GE 8 × 60 K Microarray

log2 transformed and quantile normalized

74

[GSE60432 24 h]

GPL14550

(n = 08) 4/4

851

Homo Sapiens

human placental trophoblast cells

Agilent-028004 SurePrint G3 Human GE 8 × 60 K Microarray

log2 transformed and quantile normalized

74

[GSE60432 48 h]

GPL14550

(n = 08) 4/4

851

Homo Sapiens

human placental trophoblast cells

Agilent-028004 SurePrint G3 Human GE 8 × 60 K Microarray

log2 transformed and quantile normalized

74

[GSE60432 72 h]

GPL14550

(n = 08) 4/4

851

Homo Sapiens

human placental trophoblast cells

Agilent-028004 SurePrint G3 Human GE 8 × 60 K Microarray

log2 transformed and quantile normalized

74

3

[GSE68593]

GPL20157

(n = 06) 3/3

1907

Homo Sapiens

Hepatocellular Carcinoma cells

Agilent-041686 Unrestricted Human miRNA Microarray

log2 transformed and quantile normalized

75

  1. GEO: Gene Expression Omnibus; GSE 60432 was further separated into four subgroups with 4/4 control and hypoxia exposed samples at different time points detailed in method section. These four subgroups were considered as individual datasets during meta-analysis. All the datasets used in this study were generated using a common platform; Agilent Human miRNA Microarray (probe name version).