Figure 3
Antibody responses after a single intramuscular (i.m.) or intradermal (i.d.) DNA immunization with Xcl1- and Ccl3-fusion vaccines containing influenza virus hemagglutinin. (A–C) Serum titers of IgG1 (A), IgG2a (B) and IgG2b (C) from BALB/c mice 2 weeks after a single i.m. or i.d. immunization with plasmids encoding Xcl1-HA or Ccl3-HA. D) IgG2a/IgG1 ratio of mice presented in A and B. (A–D) data presented are pooled from two independent experiments with n = 12–16 mice pr group. Statistical analysis performed using non-parametric one-way ANOVA with Dunn’s multiple comparison test, *p < 0.05, **p < 0.01, ***p < 0.001.
