Table 2 All DM patients with and without VTE.

From: Elevated plasma D-dimer levels in dermatomyositis patients with cutaneous manifestations

Ā 

all DM patients: n = 150

P-value

without VTE: n = 139

with VTE: n = 11

malignancy

n = 17

n = 1

0.758

infection

n = 22

n = 1

0.551

other CTD

n = 23

n = 3

0.366

cutaneous manifestations

n = 74

n = 4

0.281

age (years)

59.0 (51.0, 70.0)

68.0 (56.5, 76.5)

0.093

D-dimer (μg/mL)

1.28 (0.52, 3.66)

4.24 (2.15, 13.76)

<0.001

CPK (IU/L)

53 (29, 130)

57 (22, 109)

0.519

KL-6 (U/ml)

339 (243, 673)

222 (203, 240)

0.159

PLT (Ɨ104/μl)

22.3 (18.0, 29.6)

22.9 (14.2, 26.7)

0.310

PT (s)

11.2 (10.5, 11.7)

11.1 (10.5, 14.1)

0.665

APTT (s)

28.1 (25.4, 29.7)

25.8 (22.5, 30.0)

0.183

CRP (mg/dl)

0.15 (0.04, 0.49)

0.43 (0.03, 1.73)

0.272

LDH (IU/l)

244 (209, 327)

306 (252, 438)

0.032

dose of steroid (prednisolone, mg)

13.0 (5.0, 30.0)

13.0 (9.0, 35.0)

0.632

duration of steroid (years)

0.71 (0.04, 8.5)

0.28 (0.08, 5.2)

0.520

total dose of steroid (prednisolone, mg)

8610 (735, 28695)

6283 (0, 100385)

0.653

  1. DM, dermatomyositis; VTE, venous thromboembolism; CTD, connective tissue disease; CPK, creatine phosphokinase; PLT, platelet; PT, prothrombin time; APTT, activated partial thromboplastin time; CRP, C-reactive protein; LDH, lactate dehydrogenase
  2. Normal values: D-dimer, <1.00; CPK, 59–248; KL-6, 105–435; PLT, 15.8–34.8; PT, 9.8–12.1; APTT, ≤37; CRP, ≤0.14; LDH, 124–222.