Table 3 Comparison of all DM patients between the D-dimer <1 μg/mL group and D-dimer ≥1 μg/mL group.
From: Elevated plasma D-dimer levels in dermatomyositis patients with cutaneous manifestations
All DM patients: n = 150 | P-value | ||
|---|---|---|---|
D-dimer <1 μg/mL: n = 51 | D-dimer ≥1 μg/mL: n = 99 | ||
VTE | 0 | 11 | 0.016 |
malignancy | 1 | 17 | 0.007 |
infection | 3 | 20 | 0.029 |
other CTD | 12 | 14 | 0.175 |
cutaneous manifestations | 13 | 65 | <0.001 |
CPK (IU/L) | 58.0 (36.0, 104.0) | 49.0 (24.5, 150.5) | 0.260 |
KL-6 (U/ml) | 311 (222, 609) | 361 (244, 725) | 0.440 |
age (years) | 56.5 (40.5, 60.3) | 65 (53.0, 74.0) | <0.001 |
PLT (×104/μl) | 23.1 (20.4, 30.1) | 21.5 (16.7, 29.0) | 0.034 |
PT (s) | 11.2 (10.6, 11.8) | 11.2 (10.5, 11.7) | 0.635 |
APTT (s) | 28.5 (26.7, 31.5) | 27.1 (24.8, 29.3) | 0.021 |
CRP (mg/dl) | 0.070 (0.020, 0.20) | 0.20 (0.060, 1.13) | <0.001 |
LDH (IU/l) | 219 (193, 263) | 286 (214, 420) | <0.001 |
dose of steroid (prednisolone, mg) | 7.5 (5.0, 18) | 20 (8.0, 30) | 0.002 |
duration of steroid (years) | 4.9 (0.16, 11) | 0.28 (0.038, 6.5) | 0.014 |
total dose of steroid (prednisolone, mg) | 16048 (1146, 34072) | 5943 (463, 26277) | 0.070 |