Table 2 Optical coherence tomography angiography findings before and after intravitreal aflibercept treatment for diabetic macular edema.

From: Retinal Microvasculature and Visual Acuity after Intravitreal Aflibercept in Diabetic Macular Edema: An Optical Coherence Tomography Angiography Study

 

Pre-treatment

Post-treatment

P value

BCVA before treatment

 Landolt C acuity chart (mean; range)

0.52 (0.15–1.0)

0.71 (0.2–1.2)

 

 LogMAR (mean ± SD)

0.28 ± 0.23

0.15 ± 0.22

0.003

CRT (µm) (mean ± SD; range)

484 ± 133 (313–828)

275 ± 62 (190–458)

<0.001

Microaneurysm, no. (%)

 SCP

4 (17)

2 (9)

0.665

 DCP

20 (87)

13 (57)

0.049

Retinal vascular area within 3 × 3 mm2 (%)

 SCP (mean ± SD; range)

3.82 ± 0.38 (2.84–4.46)

3.82 ± 0.37 (2.98–4.46)

0.994

 DCP (mean ± SD; range)

3.88 ± 0.55 (2.46–4.66)

3.90 ± 0.62 (2.07–4.75)

0.842

FAZ area within 3 × 3 mm2 (mm2)

 SCP (mean ± SD; range)

0.41 ± 0.20 (0.18–0.69)

0.48 ± 0.24 (0.17–0.79)

0.112

 DCP (mean ± SD; range)

0.75 ± 0.34 (0.29–1.67)

0.71 ± 0.33 (0.36–1.77)

0.192

  1. BCVA, best-corrected visual acuity; logMAR, logarithm of the minimum angle of resolution; CRT, central retinal thickness; SCP, superficial capillary plexus; DCP, deep capillary plexus; FAZ, foveal avascular zone; SD, standard deviation.
Back to article page