Table 3 Optical coherence tomography angiography parameters associated with post-treatment best-corrected visual acuity after intravitreal aflibercept.

From: Retinal Microvasculature and Visual Acuity after Intravitreal Aflibercept in Diabetic Macular Edema: An Optical Coherence Tomography Angiography Study

Variable

Univariate linear regression

Regression coefficient

R2

P value

Age

−0.0014

0.006

0.732

Sex (male: 0, female: 1)

−0.179

0.138

0.081

NPDR or PDR (NPDR:0, PDR:1)

0.272

0.394

0.001

BCVA before treatment

0.625

0.452

<0.001

No. of injections

0.066

0.16

0.059

Retinal vascular area before treatment

 SCP

−0.409

0.512

<0.001

 DCP

−0.236

0.361

0.002

FAZ (mm2) before treatment

 SCP

0.187

0.029

0.438

 DCP

0.257

0.16

0.058

FAZ (mm2) after treatment

 SCP

0.266

0.084

0.179

 DCP

0.345

0.274

0.01

Retinal vascular area after treatment

 SCP

−0.489

0.717

<0.001

 DCP

−0.274

0.618

<0.001

  1. BCVA, best-corrected visual acuity; logMAR, logarithm of the minimum angle of resolution; CRT, central retinal thickness; NPDR, nonproliferative diabetic retinopathy; PDR, proliferative diabetic retinopathy; SCP, superficial capillary plexus; DCP, deep capillary plexus; FAZ, foveal avascular zone; SD, standard deviation.
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