Figure 8
From: A biophysical model explains the spontaneous bursting behavior in the developing retina
Modeling the cellular mechanisms generating bursting activity in immature SACs. (A) Experimental investigation of the cellular mechanisms involved in bursting activity by6. Gray: Fast sub-threshold oscillations and subsequent AHP generated by a short pulse of current of amplitude 150 pA and duration 60 ms. Black: Blocking of all Ca2+ related channels by Cd2+. No oscillations are exhibited. (B) Simulating the experimental conditions of 6 Gray: Reproducing fast sub-threshold oscillations and subsequent AHP emulating the experiment of 6. Application of a current step pulse of 150 pA for 60 ms. Black: Oscillations disappear when Ca2+ related conductances are set to zero.
