Figure 1

Comparison of osteocalcin production between MM-MSC (n = 4) and ND-MSC (n = 4), quantified by ELISA, on days 7, 14 and 21 of culture. The experiments were performed in technical duplicates and the results are presented as mean and standard deviation (SD). To evaluate the effect of the group over time on the osteocalcin measurements produced by MM-MSC and ND-MSC, the GEE method with gamma distribution was used. NS = Not Significant; MM-MSC = Multiple Myeloma-Mesenchymal Stem Cells; ND-MSC = Normal Donor-Mesenchymal Stem Cells.