Figure 2

Scatter plot with degree and betweenness values for all nodes of gene co-expression network. The official gene symbol of the nodes with the highest values of degree (hubs) or betweenness (bottlenecks) are highlighted in the lower right and upper left quadrants, respectively. In addition, nodes with the highest degree and highest betweenness values (high hubs) are highlighted in the upper right quadrant. Red and green symbols represent, respectively, upregulated and downregulated genes.