Figure 3
From: Imaging of nanoparticle dynamics in live and apoptotic cells using temporally-modulated polarization
Dark-field phase-modulated imaging of GNR particles enhances sensitivity and resolution. (a) A low resolution image, obtained by the conventional dark-field microscopy. (b) Applying lock-in detection, with the phase matched to that of the GNR, allows the individual GNR at the bottom of the image to be resolved. (c) Only the feature in the left upper corner of the image is visible, when the lock-in detection is applied with an opposite phase. Fitting the theoretical polarization-dependent reflectance to the experimental pixel intensities (shown in panel (d)), enhances the revealed GNRs’ signals (marked by dashed red circles).
